Domenico Ghirlandaio (1449-94) was an Italian painter of the Florentine school. In 1480 he was commissioned to paint frescoes in the Church of Ognissanti in Florence, and in the Palazzo Vecchio. In 1481 he went to Rome, where he painted his
Christ calling the first Apostles, in the Sistine Chapel. His best work is to be seen at Florence; the most famous is
The Birth of the Virgin, one of the great frescoes in the church of S. Maria Novella.